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HelpTest Code THYRO Thyrotropin Receptor Antibody, Serum
Reporting Name
Thyrotropin Receptor Ab, SUseful For
Recommended first-line test for detection of thyrotropin receptor antibodies
Differential diagnosis of etiology of thyrotoxicosis in patients with ambiguous clinical findings and/or contraindicated (eg, pregnant or breast-feeding) or nondiagnostic thyroid radioisotope scans
Diagnosing clinically suspected Graves disease (GD) (eg, extrathyroidal manifestation of GD include endocrine exophthalmos, pretibial myxedema, thyroid acropachy) in patients with normal thyroid function tests
Determining the risk of neonatal thyrotoxicosis in a fetus of a pregnant female with active or past active GD
Differential diagnosis of gestational thyrotoxicosis versus first trimester manifestation or recurrence of GD
Assessing the risk of GD relapse after antithyroid drug treatment
Performing Laboratory
Mayo Clinic Laboratories in Rochester
Specimen Required
Patient Preparation:
1. For 12 hours before specimen collection. patient should not take multivitamins or dietary supplements (eg, hair, skin, and nail supplements) containing biotin (vitamin B7).
2. Patient should not be receiving heparin treatment.
Supplies: Sarstedt Aliquot Tube, 5 mL (T914)
Collection Container/Tube:
Preferred: Serum gel
Acceptable: Red top
Submission Container/Tube: Plastic vial
Specimen Volume: 1 mL
Collection Instructions: Centrifuge and aliquot serum into a plastic vial.
CMH COLLECTION : 1.5 mL blood in a vacutainer Preferred: Red gel Acceptable: Red
Specimen Minimum Volume
0.75 mL
Specimen Stability Information
| Specimen Type | Temperature | Time |
|---|---|---|
| Serum | Refrigerated (preferred) | 7 days |
| Frozen | 90 days |
Reference Values
≤1.75 IU/L
Day(s) Performed
Monday through Saturday
CPT Code Information
83520
Report Available
1 to 3 daysReject Due To
| Gross hemolysis | Reject |
| Gross lipemia | OK |
| Gross icterus | Reject |
Method Name
Electrochemiluminescence Immunoassay