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Test Code SHBG1 Sex Hormone-Binding Globulin, Serum


Specimen Required


Collection Container/Tube:

Preferred: Serum gel

Acceptable: Red top

Submission Container/Tube: Plastic vial

Specimen Volume: 1 mL

Collection Instructions: Centrifuge and aliquot serum into a plastic vial.


Children's Mercy Hospital Note:

CMH COLLECTION: 1.5 mL in red gel vacutainer

Specimen Minimum Volume

0.5 mL

Specimen Stability Information

Specimen Type Temperature Time Special Container
Serum Refrigerated (preferred) 14 days
  Frozen  90 days
  Ambient  7 days

Useful For

Diagnosis and follow-up of women with signs or symptoms of androgen excess (eg, polycystic ovarian syndrome and idiopathic hirsutism)

 

An adjunct in monitoring sex-steroid and antiandrogen therapy

 

An adjunct in the diagnosis of disorders of puberty

 

An adjunct in the diagnosis and follow-up of anorexia nervosa

 

An adjunct in the diagnosis of thyrotoxicosis (tissue marker of thyroid hormone excess)

 

A possible adjunct in diagnosis and follow-up of insulin resistance and cardiovascular and type 2 diabetes risk assessment, particularly in women

Reject Due To

Gross hemolysis Reject
Gross lipemia OK
Gross icterus OK

Day(s) Performed

Monday through Saturday

Report Available

1 to 3 days

Reporting Name

Sex Hormone-Binding Globulin, S

Reference Values

CHILDREN:

Males

 

Tanner Stages

Mean Age

Reference Interval (nmol/L)

Stage I

10.4

17-135

Stage II

11.1

21-114

Stage III

12.7

12-138

Stage IV

14.5

7.7-67

Stage V

14.2

3.9-40

Females

Tanner Stages

Mean Age

Reference Interval (nmol/L)

Stage I

10.5

16-182

Stage II

10.9

24-121

Stage III

12.5

18-87

Stage IV

14

7.7-108

Stage V

14.9

10-79

 

ADULTS:

Males

≥18 years: 13.3-89.5 nmol/L

Females

18-46 years: 18.2-135.5 nmol/L

47-91 years: post-menopausal: 16.8-125.2 nmol/L

Method Name

Immunoenzymatic Assay

Performing Laboratory

Mayo Clinic Laboratories in Rochester

CPT Code Information

84270