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HelpTest Code SGSS Synthetic Glucocorticoid Screen, Serum
Ordering Guidance
Specimen Required
Supplies: Sarstedt Aliquot Tube, 5 mL (T914)
Collection Container/Tube:
Preferred: Red top
Acceptable: Serum gel
Submission Container/Tube: Plastic vial
Specimen Volume: 2 mL Serum
Collection Instructions: Centrifuge and aliquot serum into a plastic vial.
CMH COLLECTION: 1.5mL blood in a vacutainer Preferred: Red gel Acceptable: Red
Specimen Minimum Volume
Serum: 1.1 mL
Specimen Stability Information
| Specimen Type | Temperature | Time |
|---|---|---|
| Serum | Frozen (preferred) | 14 days |
| Refrigerated | 7 days | |
| Ambient | 24 hours |
Useful For
Confirming the presence of listed synthetic glucocorticoids in serum specimens (see Interpretation)
Confirming the cause of glucocorticoid-induced adrenal insufficiency
This test is not useful for detection of fluticasone propionate.
Reject Due To
| Gross hemolysis | OK |
| Gross lipemia | OK |
| Gross icterus | OK |
Day(s) Performed
Wednesday
Report Available
5 to 14 daysReporting Name
Synthetic Glucocorticoid Screen, SReference Values
Negative
Cutoff concentrations
Betamethasone: 0.10 mcg/dL
Budesonide: 0.20 mcg/dL
Dexamethasone: 0.10 mcg/dL
Fludrocortisone: 0.10 mcg/dL
Megestrol acetate: 0.10 mcg/dL
Methylprednisolone: 0.10 mcg/dL
Prednisolone: 0.10 mcg/dL
Prednisone: 0.10 mcg/dL
Triamcinolone acetonide: 0.10 mcg/dL
Values for normal patients not taking these synthetic glucocorticoids should be less than the cutoff concentration (detection limit).
Method Name
Liquid Chromatography Tandem Mass Spectrometry (LC-MS/MS)
Performing Laboratory
Mayo Clinic Laboratories in Rochester
CPT Code Information
80299