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HelpTest Code PQNRU Porphyrins, Quantitative, Random, Urine
Ordering Guidance
This random urine test should be ordered when the specimen will be received at Mayo Clinic Laboratories within 72 hours. If transportation may take longer than 72 hours, order both PQNU / Porphyrins, Quantitative, 24 Hour, Urine and ALAUR / Aminolevulinic Acid, Urine and follow collection guidelines.
Shipping Instructions
Ship specimen in amber bottle to protect from light.
Necessary Information
Include a list of medications the patient is currently taking.
Specimen Required
Patient Preparation: For at least 24 hours before specimen collection, patient must not consume any alcohol.
Supplies: Urine Container - Amber, 60 mL (T596)
Container/Tube: 60-mL Amber urine container
Specimen Volume: 20 to 50 mL
Collection Instructions:
1. Collect a random urine specimen.
2. No preservative3. Specimens should be protected from light and frozen immediately following collection.
CMH COLLECTION: 15mL urine in a sterile cup, protected from light
Specimen Minimum Volume
15 mL
Specimen Stability Information
| Specimen Type | Temperature | Time | Special Container |
|---|---|---|---|
| Urine | Frozen | 72 hours | LIGHT PROTECTED |
Useful For
Preferred test to begin assessment for congenital erythropoietic porphyria and porphyria cutanea tarda and during symptomatic periods for acute intermittent porphyria, hereditary coproporphyria, and variegate porphyria when specimen transport will not exceed 72 hours
This test is not useful for the diagnosis of conjugated or unconjugated hyperbilirubinemia syndromes such as Dubin Johnson syndrome or Rotor syndrome.
Reject Due To
All specimens will be evaluated at Mayo Clinic Laboratories for test suitability.Day(s) Performed
Monday through Friday
Report Available
2 to 4 daysReporting Name
Porphyrins, QN, Random, UReference Values
Uroporphyrin, Octa: ≤3.1 mcmol/mol creatinine
Heptacarboxylporphyrins: ≤0.9 mcmol/mol creatinine
Hexacarboxylporphyrins: ≤0.3 mcmol/mol creatinine
Pentacarboxylporphyrins: ≤1.2 mcmol/mol creatinine
Coproporphyrin, Tetra: ≤25.0 mcmol/mol creatinine
Porphobilinogen: ≤0.2 mmol/mol creatinine
Aminolevulinic Acid: ≤ 2.3 mmol/mol creatinine
Method Name
High-Performance Liquid Chromatography (HPLC) with Fluorometric Detection/Liquid Chromatography Tandem Mass Spectrometry (LC-MS/MS)
Performing Laboratory
Mayo Clinic Laboratories in Rochester
CPT Code Information
84110-Porphobilinogen, quantitative
84120-Porphyrins, quantitation and fractionation
82135- ALA Delta Random Urine