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HelpTest Code PQNRU Porphyrins, Quantitative, Random, Urine
Ordering Guidance
This random urine test should be ordered when the specimen will reach Mayo Clinic Laboratories within 72 hours. If transportation will take longer than 72 hours, order both PQNU / Porphyrins, Quantitative, 24 Hour, Urine and ALAUR / Aminolevulinic Acid, Urine and follow collection guidelines.
Shipping Instructions
Ship specimen in amber bottle to protect from light.
Necessary Information
Include a list of medications the patient is currently taking.
Specimen Required
Patient Preparation: Patient must not consume any alcohol for at least 24 hours before specimen collection.
Supplies: Urine Container - Amber, 60 mL (T596)
Container/Tube: Amber, 60-mL urine container
Specimen Volume: 20 to 50 mL
Collection Instructions:
1. Collect a random urine specimen.
2. No preservative necessary but pH must be above 5.0. If pH is below 5.0, specimen will be rejected.
3. Specimens should be protected from light and frozen immediately following collection.
CMH COLLECTION: 15mL urine in a sterile cup, protected from light
Specimen Minimum Volume
15 mL
Specimen Stability Information
| Specimen Type | Temperature | Time | Special Container |
|---|---|---|---|
| Urine | Frozen | 72 hours | LIGHT PROTECTED |
Testing Algorithm
The following algorithms are available:
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Useful For
Preferred test to begin assessment for congenital erythropoietic porphyria and porphyria cutanea tarda and during symptomatic periods for acute intermittent porphyria, hereditary coproporphyria, and variegate porphyria when specimen transport will not exceed 72 hours
Reject Due To
All specimens will be evaluated at Mayo Clinic Laboratories for test suitability.Day(s) Performed
Monday through Friday
Report Available
2 to 4 daysReporting Name
Porphyrins, QN, Random, UReference Values
Uroporphyrins, Octacarboxyl:
≤3.1 mcmol/mol creatinine
Heptacarboxylporphyrins:
≤0.9 mcmol/mol creatinine
Hexacarboxylporphyrins:
≤0.3 mcmol/mol creainine
Pentacarboxyporphyrins:
≤1.2 mcmol/mol creatinine
Coproporphyrin, Tetra::
≤25.0 mcmol/mol creatinine
Porphobilinogen:
≤0.2 mmol/mol creatinine
Aminolevulinic Acid
≤ 2.3 mmol/mol creatinine
Method Name
High-Performance Liquid Chromatography (HPLC) with Fluorometric Detection/Liquid Chromatography Tandem Mass Spectrometry (LC-MS/MS)
Performing Laboratory
Mayo Clinic Laboratories in Rochester
CPT Code Information
84110-Porphobilinogen, quantitative
84120-Porphyrins, quantitation and fractionation
82135- ALA Delta Random Urine