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HelpTest Code PK1 Pyruvate Kinase Enzyme Activity, Blood
Specimen Required
Collection Container/Tube:
Preferred: Yellow top (ACD solution B)
Acceptable: Lavender top (EDTA)
Specimen Volume: 6 mL
Collection Instructions:Â Send whole blood specimen in original tube. Do not aliquot.
CMH COLLECTION: 6 mL in EDTA lavendar vacutainer
Specimen Minimum Volume
1 mL
Specimen Stability Information
| Specimen Type | Temperature | Time | Special Container |
|---|---|---|---|
| Whole Blood ACD-B | Refrigerated | 20 days |
Useful For
Evaluation of nonspherocytic hemolytic anemia
Evaluation of neonatal anemia or jaundice
Evaluation of unexplained noninfectious hepatic failure
Evaluation of unexplained iron overload
Evaluation of unusually severe hemoglobin S trait
Evaluation of unusually severe glucose 6-phosphate dehydrogenase deficiency
Investigating families with pyruvate kinase deficiency to determine inheritance pattern and for genetic counseling
Reject Due To
| Gross hemolysis | Reject |
Day(s) Performed
Monday through Friday
Report Available
1 to 4 daysReporting Name
PK Enzyme Activity, BReference Values
≥12 months of age: 5.5-12.4 U/g Hb
Reference values have not been established for patients who are younger than 12 months.
Method Name
Kinetic Spectrophotometry (KS)
Performing Laboratory
Mayo Clinic Laboratories in Rochester
CPT Code Information
84220