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Test Code OROT Orotic Acid, Random, Urine


Necessary Information


Patient's age is required.



Specimen Required


Supplies: Urine Tubes, 10 mL (T068)

Container/Tube: Plastic, 10-mL urine tube

Specimen Volume: 3 mL

Collection Instructions:

1. Collect a random urine specimen.

2. No preservative needed.


Children's Mercy Hospital Note:

CMH COLLECTION: 10 mL in sterile cup

Specimen Minimum Volume

2 mL

Specimen Stability Information

Specimen Type Temperature Time
Urine Frozen 90 days

Useful For

Evaluation of the differential diagnosis of hyperammonemia and hereditary orotic aciduria

 

Sensitive indicator of ornithine transcarbamylase (OTC) activity after administration of allopurinol or a protein load to identify OTC carriers

Reject Due To

  All specimens will be evaluated at Mayo Clinic Laboratories for test suitability.

Day(s) Performed

Tuesday, Thursday

Report Available

3 to 7 days

Reporting Name

Orotic Acid, U

Reference Values

≤6 years: ≤4 mmol/mol creatinine

7-18 years: ≤3 mmol/mol creatinine

≥19 years: 5 mmol/mol creatinine

Method Name

Liquid Chromatography Tandem Mass Spectrometry (LC-MS/MS)

Performing Laboratory

Mayo Clinic Laboratories in Rochester

CPT Code Information

83921