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HelpTest Code NSESF Neuron-Specific Enolase (NSE), Spinal Fluid
Specimen Required
Container/Tube: Sterile vial
Specimen Volume: 0.5 mL
Children's Mercy Hospital
Note:
CMH COLLECTION: 0.5 mL in sterile cup
Specimen Minimum Volume
0.3 mL
Specimen Stability Information
| Specimen Type | Temperature | Time | Special Container |
|---|---|---|---|
| CSF | Refrigerated (preferred) | 15 days | |
| Ambient | 72 hours |
Useful For
An auxiliary test in the diagnosis of Creutzfeldt-Jakob disease
An auxiliary test in the diagnosis of small cell lung carcinoma metastasis to central nervous system or leptomeninges
Reject Due To
| Gross hemolysis | Reject |
| Gross lipemia | OK |
| Gross icterus | Reject |
Day(s) Performed
Monday through Saturday
Report Available
1 to 3 daysReporting Name
Neuron Specific Enolase, CSFReference Values
Normal: ≤15 ng/mL
Indeterminate: 15-30 ng/mL
Elevated: >30 ng/mL
Elevated results may indicate the need for additional workup. Possible causes may be neuron-specific enolase-secreting central nervous system/leptomeningeal tumor or rapid neuronal destruction from a variety of causes. In the context of dementia, elevated results may be suggestive of Creutzfeldt-Jakob disease.
Method Name
Homogeneous Time-Resolved Fluorescence
Performing Laboratory
Mayo Clinic Laboratories in Rochester
CPT Code Information
83520