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HelpTest Code NSE Neuron-Specific Enolase, Serum
Specimen Required
Collection Container/Tube:
Preferred: Red top
Acceptable: Serum gel
Submission Container/Tube: Plastic vial
Specimen Volume: 0.5 mL
Collection Instructions:
1. Specimens should not be transported by tube system prior to centrifugation.
2. Centrifuge and aliquot serum into a plastic vial.
CMH COLLECTION: 1 mL red vacutainer
Specimen Minimum Volume
0.3 mL
Specimen Stability Information
| Specimen Type | Temperature | Time | Special Container |
|---|---|---|---|
| Serum | Refrigerated (preferred) | 7 days | |
| Ambient | 5 days |
Useful For
A follow-up marker in patients with neuron-specific enolase-secreting tumors of any type
An auxiliary test in the diagnosis of small cell lung carcinoma
An auxiliary test in the diagnosis of carcinoids, islet cell tumors, and neuroblastomas
An auxiliary tool in the assessment of comatose patients
Reject Due To
| Gross hemolysis | Reject |
| Gross lipemia | OK |
| Gross icterus | Reject |
| Hemolysis at any level | Reject |
Day(s) Performed
Monday through Saturday
Report Available
1 to 3 daysReporting Name
Neuron Specific Enolase, SReference Values
≤15 ng/mL
Serum markers are not specific for malignancy, and values may vary by method.
Method Name
Homogeneous Time-Resolved Fluorescence
Performing Laboratory
Mayo Clinic Laboratories in Rochester
CPT Code Information
83520