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HelpTest Code NMOFC Neuromyelitis Optica (NMO)/Aquaporin-4-IgG Fluorescence-Activated Cell Sorting (FACS) Assay, Spinal Fluid
Ordering Guidance
Necessary Information
Include relevant clinical information, name, phone number, mailing address, and e-mail address (if applicable) of ordering physician.
Specimen Required
Collection Container/Tube: Sterile vial
Specimen Volume: 3 mL
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CMH COLLECTION: 2 mL in sterile cup
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Specimen Minimum Volume
2 mL
Specimen Stability Information
| Specimen Type | Temperature | Time | Special Container |
|---|---|---|---|
| CSF | Refrigerated (preferred) | 28 days | |
| Frozen | 28 days | ||
| Ambient | 72 hours |
Testing Algorithm
When the results of this assay require further evaluation, NMOTC / Neuromyelitis Optica (NMO)/Aquaporin-4-IgG Fluorescence-Activated Cell Sorting (FACS) Assay Titer, Spinal Fluid will be performed at an additional charge.
Reflex Tests
| Test ID | Reporting Name | Available Separately | Always Performed |
|---|---|---|---|
| NMOTC | NMO/AQP4 FACS Titer, CSF | No | No |
Useful For
Diagnosis of a neuromyelitis optica spectrum disorder (NMOSD)
Diagnosis of autoimmune AQP4 channelopathy
Distinguishing NMOSD from multiple sclerosis early in the course of disease
Reject Due To
| Gross hemolysis | OK |
| Gross lipemia | OK |
| Gross icterus | OK |
Day(s) Performed
Monday, Tuesday, Thursday
Report Available
5 to 8 daysReporting Name
NMO/AQP4 FACS, CSFReference Values
Negative
Method Name
Flow Cytometry
Performing Laboratory
Mayo Clinic Laboratories in Rochester
CPT Code Information
86053
86053-titer (if appropriate)