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Test Code MPU Monoclonal Protein Studies, 24 Hour, Urine


Shipping Instructions


Refrigerate specimen during collection and send refrigerated.



Necessary Information


24-Hour volume (in milliliters) is required.



Specimen Required


Supplies: Urine Container, 60 mL (T313)

Submission Container/Tube: Plastic, 60-mL urine bottle

Specimen Volume: 50 mL

Collection Instructions:

1. Collect urine for 24 hours.

2. Aliquot between 30 mL and 50 mL urine into plastic, 60-mL urine bottle.

Additional Information: See Urine Preservatives-Collection and Transportation for 24-Hour Urine Specimens for multiple collections.


Children's Mercy Hospital Note:

CMH COLLECTION : 24 hour urine in urine jug

Useful For

Monitoring patients with monoclonal gammopathies

Profile Information

Test ID Reporting Name Available Separately Always Performed
MPTU M-protein Mass-Fix, 24 HR, U No Yes
PEU Protein Electrophoresis, 24 Hr, U No Yes
PTU3 Protein, Total, 24 HR, U Yes, (Order PTU) Yes

Testing Algorithm

The following algorithms are available:

-Amyloidosis: Laboratory Approach to Diagnosis

-Multiple Myeloma: Laboratory Screening

Method Name

PTU: Turbidimetry

PEU: Agarose Gel Electrophoresis

MPTU: Matrix-Assisted Laser Desorption/Ionization Time-of-Flight Mass Spectrometry (MALDI-TOF MS)

Reporting Name

M-protein Studies, 24 HR, U

Specimen Minimum Volume

30 mL

Specimen Stability Information

Specimen Type Temperature Time Special Container
Urine Refrigerated (preferred) 14 days
  Frozen  5 days
  Ambient  24 hours

Reject Due To

  All specimens will be evaluated at Mayo Clinic Laboratories for test suitability.

Reference Values

PROTEIN, TOTAL:

<229 mg/24 hours

Reference values have not been established for patients <18 years of age.

 

ELECTROPHORESIS, PROTEIN:

The following fractions, if present, will be reported as mg/24 hours:

Albumin

Alpha-1 globulin

Alpha-2 globulin

Betaglobulin

Gamma globulin

 

MASS-FIX M-PROTEIN ISOTYPE:

M-protein Isotype MS:

No monoclonal protein detected

 

Flag M-protein Isotype MS:

Negative

Day(s) Performed

Monday through Friday

Report Available

4 to 6 days

Performing Laboratory

Mayo Clinic Laboratories in Rochester

CPT Code Information

84156

84166

0077U

Urine Preservative Collection Options

Note: The addition of preservative or application of temperature controls must occur within 4 hours of completion of the collection.

Ambient

OK

Refrigerate

Preferred

Frozen

OK

50% Acetic Acid

No

Boric Acid

No

Diazolidinyl Urea

OK

6M Hydrochloric Acid

No

6M Nitric Acid

No

Sodium Carbonate

No

Thymol

OK

Toluene

No