Test Code MNS Manganese, Serum
Specimen Required
Patient Preparation: High concentrations of gadolinium, iodine, and barium are known to interfere with most metal tests. If gadolinium-, iodine, or barium-containing contrast media has been administered, a specimen should not be collected for 96 hours.
Supplies: Metal Free Specimen Vial (T173)
Collection Container/Tube: Plain, royal blue-top Vacutainer plastic trace element blood collection tube
Submission Container/Tube: 7-mL Mayo metal-free, screw-capped, polypropylene vial
Specimen Volume: 0.3 mL
Collection Instructions:
1. Allow the specimen to clot for 30 minutes, and then centrifuge to separate serum from the cellular fraction. Serum must be removed from cellular fraction within 4 hours of collection. Avoid hemolysis.
2. Remove the stopper. Carefully pour specimen into a Mayo metal-free, polypropylene vial, while avoiding transfer of the cellular components of blood. Do not insert a pipet into the serum to accomplish transfer, and do not ream the specimen with a wooden stick to assist with serum transfer.
3. See Metals Analysis Specimen Collection and Transport for complete instructions.
CMH COLLECTION: 2 mL in Serum Royal (Check label - Red edge and Serum)
Specimen Minimum Volume
0.2 mL
Specimen Stability Information
Specimen Type | Temperature | Time | Special Container |
---|---|---|---|
Serum | Refrigerated (preferred) | 28 days | METAL FREE |
Ambient | 28 days | METAL FREE | |
Frozen | 28 days | METAL FREE |
Useful For
Monitoring manganese exposure using serum specimens
Nutritional monitoring
Reject Due To
Gross hemolysis | Reject |
Gross lipemia | OK |
Gross icterus | OK |
Day(s) Performed
Tuesday
Report Available
2 to 8 daysReporting Name
Manganese, SReference Values
0-17 years: Not established
≥18 years: 0.5-1.2 ng/mL
Method Name
Triple-Quadrupole Inductively Coupled Plasma-Mass Spectrometry (ICP-MS/MS)
Performing Laboratory
Mayo Clinic Laboratories in RochesterCPT Code Information
83785