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Test Code MMAS Methylmalonic Acid, Quantitative, Serum


Specimen Required


Collection Container/Tube:

Preferred: Serum gel

Acceptable: Red top

Submission Container/Tube: Plastic vial

Specimen Volume:1.5 mL

Collection Instructions: Centrifuge and aliquot serum into a plastic vial.


Children's Mercy Hospital Note:

CMH COLLECTION: 2 mL in red gel vacutainer

Specimen Minimum Volume

0.5 mL

Specimen Stability Information

Specimen Type Temperature Time Special Container
Serum Refrigerated (preferred) 48 days
  Ambient  48 days
  Frozen  48 days

Useful For

Evaluating children with signs and symptoms of methylmalonic acidemia using serum specimens

 

Evaluating individuals with signs and symptoms associated with a variety of causes of vitamin B12 (cobalamin) deficiency

Reject Due To

Gross hemolysis OK
Gross lipemia OK
Gross icterus OK

Day(s) Performed

Monday through Friday

Report Available

3 to 5 days

Reporting Name

Methylmalonic Acid, QN, S

Reference Values

≤0.40 nmol/mL

Method Name

Liquid Chromatography Tandem Mass Spectrometry (LC-MS/MS)

Performing Laboratory

Mayo Clinic Laboratories in Rochester

CPT Code Information

83921