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HelpTest Code LEFLU Leflunomide Metabolite (Teriflunomide), Serum
Specimen Required
Supplies: Sarstedt Aliquot Tube, 5 mL (T914)
Collection Container/Tube:
Preferred: Red top
Acceptable: Serum gel
Submission Container/Tube: Plastic vial
Specimen Volume: 1 mL
Collection Instructions:
1. Draw blood no sooner than 12 hours (trough value) after last dose.
2. Within 2 hours of collection, centrifuge and aliquot serum into a plastic vial.
Children's Mercy Hospital
Note:
CMH COLLECTION: 3 mL in red gel vacutainer
Specimen Minimum Volume
0.3 mL
Specimen Stability Information
| Specimen Type | Temperature | Time | Special Container |
|---|---|---|---|
| Serum Red | Ambient (preferred) | 28 days | |
| Frozen | 28 days | ||
| Refrigerated | 28 days |
Useful For
Therapeutic monitoring of patients actively taking leflunomide
Assessment of elimination in patients requiring enhanced elimination of the drug
Reject Due To
| Gross hemolysis | OK |
| Gross lipemia | OK |
| Gross icterus | OK |
Day(s) Performed
Monday, Wednesday, Friday
Report Available
3 to 5 daysReporting Name
Leflunomide Metabolite, SReference Values
Therapeutic: >40 mcg/mL
Elimination: <0.020 mcg/mL
Method Name
High-Turbulence Liquid Chromatography Mass Spectrometry (HTLC-MS/MS)
Performing Laboratory
Mayo Clinic Laboratories in Rochester
CPT Code Information
80193