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HelpTest Code LAMO Lamotrigine, Serum
Specimen Required
Supplies: Sarstedt Aliquot Tube, 5 mL (T914)
Collection Container/Tube:
Preferred: Red top
Acceptable: Serum gel
Submission Container/Tube: Plastic vial
Specimen Volume: 1 mL
Collection Instructions:
1. Collect blood immediately before next scheduled dose.
2. For sustained-release formulations only, collect blood a minimum of 12 hours after last dose.
3. Centrifuge within 2 hours of collection
4. For red-top tubes, immediately aliquot serum into a plastic vial.
5. For serum gel tubes, aliquot serum into a plastic vial within 24 hours of collection.
CMH COLLECTION: 2 mL in red gel vacutainer
Specimen Minimum Volume
0.5 mL
Specimen Stability Information
| Specimen Type | Temperature | Time | Special Container |
|---|---|---|---|
| Serum | Refrigerated (preferred) | 28 days | |
| Ambient | 28 days | ||
| Frozen | 28 days |
Useful For
Monitoring serum concentration of lamotrigine
Assessing compliance
Adjusting lamotrigine dose in patients receiving other anticonvulsant drugs that interact pharmacokinetically with lamotrigine
Reject Due To
| Gross hemolysis | OK |
| Gross lipemia | OK |
| Gross icterus | OK |
Day(s) Performed
Monday through Sunday
Report Available
Same day/1 to 2 daysReporting Name
Lamotrigine, SReference Values
Patients receiving therapeutic doses usually have lamotrigine concentrations of 3.0-15.0 mcg/mL.
Method Name
Liquid Chromatography-Tandem Mass Spectrometry (LC-MS/MS)
Performing Laboratory
Mayo Clinic Laboratories in Rochester
CPT Code Information
80175