Additional Information

Advantages: Evaluates hundreds of different genetic conditions, including aneuploidy. Detects large and small deletions and duplications, which may not be detected by conventional chromosome analysis. Detects regions of homozygosity. DNA isolated from fresh tissue. Limitations: Cannot identify truly balanced chromosomal aberrations, i.e., balanced translocations, inversion, insertions, etc. Cannot detect point mutations or epigenetic changes. Cannot detect genomic imbalances in regions not represented on the microarray. Low-level mosaicism may not be detected.