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Chromosome Analysis, products of conception

Collection Requirements

Source: products of conception
Container: sterile cup or tube with sterile transport medium or sterile saline

  • For early pregnancy loss (12 weeks or less), send the entire sac
  • For pregnancy loss (>12 weeks), collect chorionic villi or chorion,fetal membranes, rib cartilage, muscle, tendon, or skin; keeping each speicmen type type in separate containers
  • If the specimen is from a stillborn, 2-3 mL blood in a Sodium heparin green and chorion is preferred
  • If an autopsy is not being performed, a small section of underarm skin with dermal tissue should be collected after cleansing the skin with alcohol, followed by sterile saline. A 1 cm3 piece of skin should be obtained.

Special Instructions

  • Transport at room temperature; avoid fluctuating temperatures (hot or cold)
  • Specimen must be processed within 24 hours of collection
  • Contact Genetics for collection materials
  • Use the Prenatal and Pregnancy Loss Cytogenetics Requisition

Turn Around Time

28 days

Availability

Routine

Lab Processing Instructions

Specimen: tissue
Room temperature

Performing Laboratory

Genetics

Adele Hall Lab Section

Cytogenetics

Instrumentation/Methodology

Long term cell/monolayer cultures with GTG banding

Additional Information

Indications for testing: History of multiple spontaneous abortions without evidence of a clear reason for loss of pregnancy; Previous pregnancy or family history of a chromosome abnormality; patient carrying a known translocation

Reference Ranges

See interpretive report

CPT

88262, 88233