Chromosome Analysis, chorionic villi
Collection Requirements
Source: chorionic villus sampling
Container: sterile specimen cup or tube with
sterile transport medium
Volume: at least 50 mg of chorionic villus
sampling
Special Instructions
- Transport at room temperature; avoid fluctuating temperatures (hot or cold)
- Specimen must be processed within 24 hours of collection
- Contact Genetics for collection materials
- Use the Prenatal and Pregnancy Loss Cytogenetics Requisition
Turn Around Time
14 days
Availability
Routine
Lab Processing Instructions
Specimen: chorionic villi
Room temperature
Performing Laboratory
Genetics
Adele Hall Lab Section
Cytogenetics
Instrumentation/Methodology
Villi are dissected from maternal decidua followed by cell culture. The cells are processed by exposure to colcemid and hypotonic solution, then fixed. Slides are prepared and GTG banded. Chromosomes analysis and image captured are performed on a computerized imaging system.
Additional Information
Indications for testing: advanced maternal age (>35 years of age); Previous pregnancy with a chromosome abnormality; Parent carrying a known translocation; Abnormal ultrasound findings; Abnormal NIPS
Reference Ranges
See interpretive report
CPT
88267, 88235, 88261