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HelpTest Code GDF15 Growth Differentiation Factor 15, Plasma
Specimen Required
Collection Container/Tube:
Preferred: Lavender top (EDTA)
Acceptable: Green top (sodium heparin)
Submission Container/Tube: Plastic vial
Specimen Volume: 0.5 mL
Collection Instructions:
1. Draw blood and centrifuge immediately.
2. Aliquot plasma into plastic vial.
3. Do not expose specimen to heat or direct sunlight.
CMH COLLECTION: 1mL blood in a vacutainer Preferred: EDTA lavender Acceptable: Sodium heparin green
Specimen Minimum Volume
0.2 mL
Specimen Stability Information
| Specimen Type | Temperature | Time |
|---|---|---|
| Plasma | Refrigerated (preferred) | 90 days |
| Frozen | 90 days | |
| Ambient | 28 days |
Testing Algorithm
For information see Epilepsy: Unexplained Refractory and/or Familial Testing Algorithm
Useful For
A circulating biomarker in myopathy-related mitochondrial disease as well as other conditions
Investigation of patients suspected of having a mitochondrial myopathy
This assay is not suitable for carrier detection.
Reject Due To
| Gross hemolysis | OK |
| Gross lipemia | OK |
| Gross icterus | OK |
Day(s) Performed
Wednesday, Friday
Report Available
2 to 6 daysReporting Name
Growth Differentiation Factor 15, PReference Values
3 months* and older: ≤750 pg/Ml
*This test is not recommended for infants younger than 3 months of age due to the high levels of growth differentiation factor 15 contributed from the placenta during pregnancy.
Method Name
Enzyme-Linked Immunosorbent Assay (ELISA)
Performing Laboratory
Mayo Clinic Laboratories in Rochester
CPT Code Information
83520