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Test Code GBM Glomerular Basement Membrane Antibodies, IgG, Serum


Ordering Guidance


If patient is being evaluated for autoimmune skin disease, order CIFS / Cutaneous Immunofluorescence Antibodies (IgG), Serum for evaluation of anti-intercellular substance (ICS) and antibasement membrane zone (BMZ) antibodies.



Specimen Required


Supplies: Sarstedt Aliquot Tube 5 mL (T914)

Collection Container/Tube:

Preferred: Serum gel

Acceptable: Red top

Submission Container/Tube: Plastic vial

Specimen Volume: 0.5 mL

Collection Instructions: Centrifuge and aliquot serum into a plastic vial.


Children's Mercy Hospital Note:

CMH COLLECTION: 1 mL in red gel vacutainer

Specimen Minimum Volume

0.35 mL

Specimen Stability Information

Specimen Type Temperature Time Special Container
Serum Refrigerated (preferred) 21 days
  Frozen  21 days

Useful For

Evaluating patients with clinical features of anti-glomerular basement disease, including rapidly progressive glomerulonephritis or pulmonary hemorrhage

Reject Due To

Gross hemolysis Reject
Gross lipemia Reject
Gross icterus OK

Day(s) Performed

Monday through Friday

Report Available

2 to 3 days

Reporting Name

Glomerular Basement Membrane IgG Ab

Reference Values

<1.0 U (negative)

≥1.0 U (positive)

Reference values apply to all ages.

Method Name

Multiplex Flow Immunoassay

Performing Laboratory

Mayo Clinic Laboratories in Rochester

CPT Code Information

83516