Test Code G6PD1 Glucose 6-Phosphate Dehydrogenase Enzyme Activity, Blood
Specimen Required
Collection Container/Tube:
Preferred: Yellow top (ACD solution B)
Acceptable: Lavender top (EDTA) or yellow top (ACD solution A)
Specimen Volume: 6 mL
Collection Instructions: Send specimen in original tube. Do not aliquot.
CMH COLLECTION: 6 mL in EDTA lavender vacutainer
Specimen Minimum Volume
1 mL
Specimen Stability Information
Specimen Type | Temperature | Time | Special Container |
---|---|---|---|
Whole Blood ACD-B | Refrigerated | 20 days |
Testing Algorithm
The following are available:
-Glucose-6-Phosphate Dehydrogenase (G6PD) Deficiency Diagnostic Algorithm
-Glucose-6-Phosphate Dehydrogenase (G6PD) Genotyping Interpretive Algorithm
-Newborn Screen Follow-up for Glucose-6-Phosphate Dehydrogenase (G6PD) Deficiency
-Newborn Screening Act Sheet Glucose-6-Phosphate Dehydrogenase Deficiency
Useful For
Evaluation of individuals with episodic or chronic Coombs-negative nonspherocytic hemolytic anemia
Rapid testing to assess glucose 6-phosphate dehydrogenase (G6PD) enzyme capacity prior to rasburicase or other therapies that may cause hemolysis or methemoglobinemia in G6PD deficient patients
May aid in the creation of a comprehensive patient profile and can ensure appropriate patient monitoring for developing anemia
Reject Due To
Gross hemolysis | Reject |
Day(s) Performed
Monday through Friday
Report Available
1 to 4 daysReporting Name
G6PD Enzyme Activity, BReference Values
≥12 months of age: 8.0-11.9 U/g Hb
Reference values have not been established for patients who are less than 12 months of age.
Method Name
Kinetic Spectrophotometry
Performing Laboratory
Mayo Clinic Laboratories in RochesterCPT Code Information
82955
Special Instructions
- Newborn Screening Act Sheet Glucose-6-Phosphate Dehydrogenase Deficiency
- Newborn Screen Follow-up for Glucose-6-Phosphate Dehydrogenase (G6PD) Deficiency
- Glucose-6-Phosphate Dehydrogenase (G6PD) Genotyping Interpretive Algorithm
- Glucose-6-Phosphate Dehydrogenase (G6PD) Deficiency Diagnostic Algorithm