Test Code FLUC 5-Flucytosine, Serum
Specimen Required
Supplies: Sarstedt Aliquot Tube, 5 mL (T914)
Collection Container/Tube:
Preferred: Red top
Acceptable: Serum gel
Submission Container/Tube: Plastic vial
Specimen Volume: 0.5 mL
Collection Instructions:
1. Serum for a peak level should be collected 1 to 2 hours after oral dose or 30 minutes after intravenous infusion. Trough specimens should be collected immediately prior to next scheduled dose.
2. Within 2 hours of collection, centrifuge, and aliquot serum to plastic vial.
CMH COLLECTION: 3 mL in red vacutainer
Peak level: Draw 30 minutes after completion of infusion of an IV dose or 1-2 hr after oral dose.
Specimen Minimum Volume
0.3 mL
Specimen Stability Information
Specimen Type | Temperature | Time | Special Container |
---|---|---|---|
Serum | Refrigerated (preferred) | 28 days | |
Ambient | 28 days | ||
Frozen | 28 days |
Useful For
Monitoring serum concentration during therapy
Evaluating potential toxicity
May aid in evaluating patient compliance
Reject Due To
Gross hemolysis | OK |
Gross lipemia | OK |
Gross icterus | OK |
Day(s) Performed
Tuesday, Thursday
Report Available
3 to 8 daysReporting Name
5-Flucytosine, SReference Values
Therapeutic concentration:
Peak >25.0 mcg/mL (difficult infections may require higher concentrations)
Toxic concentration:
Peak >100.0 mcg/mL
Method Name
Liquid Chromatography Tandem Mass Spectrometry (LC-MS/MS)
Performing Laboratory
Mayo Clinic Laboratories in RochesterCPT Code Information
80299