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Test Code FET Iron, Liver Tissue

Important Note

CMH Cerner Order: Ref Misc


Necessary Information


Patient's date of birth is required to calculate iron index.



Specimen Required


Supplies: Metal Free Specimen Vial (T173)

Container/Tube:

Preferred: Mayo metal-free specimen vial

Acceptable: Paraffin block, with no more than 1 or 2 cuts previously made

Specimen Volume: 2 mg

Collection Instructions: Two mg of liver tissue are required. This is typically a piece of tissue from a 22-gauge needle biopsy at least 2 cm long. If an 18-gauge needle is used, the tissue must be at least 1 cm in length.

Additional Information: Paraffin blocks will be returned 7 days after analysis is complete.


Specimen Minimum Volume

Needle biopsy: See Specimen Required; 2 mm x 2 mm (punch): 0.3 mg by dry weight

Specimen Stability Information

Specimen Type Temperature Time Special Container
Liver Tissue Refrigerated (preferred)
  Ambient 
  Frozen 

Testing Algorithm

For more information see Hereditary Hemochromatosis Algorithm.

Useful For

Diagnosis of hemochromatosis using liver tissue specimens

Reject Due To

All specimens will be evaluated at Mayo Clinic Laboratories for test suitability.

Day(s) Performed

Monday, Thursday

Report Available

3 to 6 days

Reporting Name

Iron, Liver Ts

Reference Values

Iron

Males: 200-2,400 mcg/g dry weight

Females: 200-1,800 mcg/g dry weight

 

Iron Index

≥13 years: <1.0 mcmol/g/year

Reference values have not been established for patients that are younger than 13 years.

Method Name

Inductively Coupled Plasma Mass Spectrometry (ICP-MS)

Performing Laboratory

Mayo Clinic Laboratories in Rochester

CPT Code Information

83540