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HelpTest Code EEEV1 Red Blood Cell (RBC) Enzyme Evaluation, Blood
Necessary Information
Metabolic Hematology Patient Information (T810) is strongly recommended and should include clinical history. Testing may proceed without this information, however if the information requested is received, it allows for a more complete interpretation.
Specimen Required
Container/Tube:
Preferred: Yellow top (ACD solution B)
Acceptable: Yellow top (ACD solution A)
Specimen Volume: 12 mL
Collection Instructions: Send whole blood specimen in original tube. Do not aliquot.
CMH COLLECTION: 5mL blood in an ACD Yellow solution B vacutainer
Specimen Minimum Volume
5 mL
Specimen Stability Information
| Specimen Type | Temperature | Time | Special Container |
|---|---|---|---|
| Whole Blood ACD-B | Refrigerated | 11 days |
Testing Algorithm
This is a consultative evaluation in which the case will be evaluated at Mayo Clinic Laboratories.
Useful For
Identifying defects of red blood cell enzyme metabolism
Evaluating patients with Coombs-negative hemolytic anemia
Reject Due To
| Gross hemolysis | Reject |
Day(s) Performed
Tuesday, Thursday
Report Available
2 to 13 daysReporting Name
RBC Enzyme EvaluationReference Values
Definitive results and an interpretive report will be provided.
Method Name
EEEVI: Medical Interpretation
G6PDC, GPIC, PKC, HKC, AKC, PFKC, PGKC, TPIC, GSH, P5NT: Kinetic Spectrophotometry
Performing Laboratory
Mayo Clinic Laboratories in Rochester
CPT Code Information
82955-G6PD Enzyme Activity
84087-Glucose phosphate isomerase
84220-Pyruvate Kinase Enzyme Activity
82657-Hexokinase
82657-Adenylate Kinase
82657-Phosphofructokinase
82657-Phosphoglycerate Kinase
82657-Triosephosphate Isomerase
82978-Glutathione
83915-Pyrimidine 5' Nucleotidase
Profile Information
| Test ID | Reporting Name | Available Separately | Always Performed |
|---|---|---|---|
| EEEVI | Erythrocyte Enzyme Interpretation | No | Yes |
| G6PDC | G6PD Enzyme Activity, B | Yes, (Order G6PD1) | Yes |
| PKC | PK Enzyme Activity, B | Yes, (Order PK1) | Yes |
| GPIC | Glucose Phosphate Isomerase, B | Yes, (Order GPI1) | Yes |
| HKC | Hexokinase, B | Yes, (Order HK1) | Yes |
| AKC | Adenylate Kinase, B | Yes, (Order AK1) | Yes |
| PFKC | Phosphofructokinase, B | Yes, (Order PFK1) | Yes |
| PGKC | Phosphoglycerate Kinase, B | Yes, (Order PGK1) | Yes |
| TPIC | Triosephosphate Isomerase, B | Yes, (Order TPI1) | Yes |
| GSH | Glutathione, B | Yes | Yes |
| P5NT | Pyrimidine 5' Nucleotidase, B | Yes | Yes |