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HelpPhenylalanine Level
Collection Requirements
Source: Dried blood spot on filter paper
(S&S type 903 or equivalent) obtained from Toxicology
Home Collection:
- Completely fill at least 2 circles
- Blood spots should be completely dry before they are shipped (4 – 6 hours)
Source: blood
Container:
- Preferred : Lithium heparin mint green gel
- Acceptable: Red gel
Volume: 1 mL in a vacutainer or 600 uL in microtainer
Availability
Routine
Turn Around Time
1-5 days
Testing performed on Tuesday and Thursday
Must be received in the Toxicology Lab by 7:00 a.m. Tuesday or Thursday to be included in the batch
Lab Processing Instructions
Specimen: Dried blood spot on filter paper
Room temperature
Specimen: plasma or serum
Spin, separate, and refrigerate
Performing Laboratory
Adele Hall
Adele Hall Lab Section
Biochemical Genetics
Additional Information
Phenylalanine measurement is used in the diagnosis of hyperphenylalanine and PKU
Instrumentation/Methodology
High Performance Liquid Chromatography/Tandem Mass Spectrometry (LC-MS/MS)
Reference Ranges
| Age | Reference Range (mg/dL) | Reference Range (umol/L) |
|---|---|---|
| Premature infant | 1.6 - 3.5 | 98 - 213 |
| 0-1 month | 0.6 - 2.3 | 38 - 137 |
| 1 month - 2 years | 0.5 - 1.2 | 31 - 75 |
| 2-18 years | 0.4 - 1.5 | 26 - 91 |
| >18 years | 0.6 - 1.4 | 35 - 85 |
CPT
84030