Test Code CLOBZ Clobazam and Metabolite, Serum
Specimen Required
Supplies: Sarstedt Aliquot Tube, 5 mL (T914)
Collection Container/Tube: Red top (serum gel/SST are not acceptable)
Submission Container/Tube: Plastic vial
Specimen Volume: 0.5 mL
Collection Instructions:
1. Collect blood immediately before next scheduled dose.
2. Within 2 hours of collection, centrifuge and aliquot serum into a plastic vial.
Additional Information: Trough specimens are recommended as therapeutic ranges are based on specimens collected at trough (ie, immediately before the next dose).
CMH COLLECTION: 2 mL in red vacutainer
Specimen Minimum Volume
0.35 mL
Specimen Stability Information
Specimen Type | Temperature | Time | Special Container |
---|---|---|---|
Serum Red | Refrigerated (preferred) | 28 days | |
Ambient | 28 days | ||
Frozen | 28 days |
Useful For
Monitoring clobazam therapy
Reject Due To
Gross hemolysis | OK |
Gross lipemia | OK |
Gross icterus | OK |
Day(s) Performed
Monday through Friday
Report Available
Same day/1 to 5 daysReporting Name
Clobazam and metabolite, SReference Values
Clobazam
Therapeutic Range: 30-300 ng/mL
N-desmethylclobazam (Norclobazam)
Therapeutic Range: 300-3,000 ng/mL
Method Name
Liquid Chromatography Tandem Mass Spectrometry (LC-MS/MS)
Performing Laboratory
Mayo Clinic Laboratories in RochesterCPT Code Information
80339 (G0480 if appropriate)