Sign in →

Test Code CLOBZ Clobazam and Metabolite, Serum


Specimen Required


Supplies: Sarstedt Aliquot Tube, 5 mL (T914)

Collection Container/Tube: Red top (serum gel/SST are not acceptable)

Submission Container/Tube: Plastic vial

Specimen Volume: 0.5 mL

Collection Instructions:

1. Collect blood immediately before next scheduled dose.

2. Within 2 hours of collection, centrifuge and aliquot serum into a plastic vial.

Additional Information: Trough specimens are recommended as therapeutic ranges are based on specimens collected at trough (ie, immediately before the next dose).


Children's Mercy Hospital Note:

CMH COLLECTION: 2 mL in red vacutainer

Specimen Minimum Volume

0.35 mL

Specimen Stability Information

Specimen Type Temperature Time Special Container
Serum Red Refrigerated (preferred) 28 days
  Ambient  28 days
  Frozen  28 days

Useful For

Monitoring clobazam therapy

Reject Due To

Gross hemolysis OK
Gross lipemia OK
Gross icterus OK

Day(s) Performed

Monday through Friday

Report Available

Same day/1 to 5 days

Reporting Name

Clobazam and metabolite, S

Reference Values

Clobazam

Therapeutic Range: 30-300 ng/mL

 

N-desmethylclobazam (Norclobazam)

Therapeutic Range: 300-3,000 ng/mL

Method Name

Liquid Chromatography Tandem Mass Spectrometry (LC-MS/MS)

Performing Laboratory

Mayo Clinic Laboratories in Rochester

CPT Code Information

80339 (G0480 if appropriate)