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Test Code CASF IgG/Albumin Ratio, Spinal Fluid

Important Note

CMH Cerner Order: Ref Misc


Ordering Guidance


The cerebrospinal fluid (CSF) index in which the CSF IgG/albumin ratio is compared to the serum IgG/albumin ratio aids in the diagnosis of individuals with multiple sclerosis. See SFIG / Cerebrospinal Fluid IgG Index Profile, Serum and Spinal Fluid.



Specimen Required


Specimen Type: Spinal fluid (CSF)

Container/Tube: Sterile vial

Specimen Volume: 1 mL

Collection Instructions:

1. Submit CSF from collection vial number 2 (preferred, not required).

2. Label specimen as CSF.


Children's Mercy Hospital Note:

CMH COLLECTION: 0.5mL CSF in a sterile cup

Specimen Minimum Volume

1 mL

Specimen Stability Information

Specimen Type Temperature Time
CSF Refrigerated (preferred) 28 days
  Frozen  28 days
  Ambient  14 days

Useful For

Assessment of cerebrospinal fluid (CSF) IgG/albumin ratio in the absence of a paired CSF and serum specimen

Reject Due To

Gross hemolysis OK
Gross lipemia OK
Gross icterus OK

Day(s) Performed

Monday through Friday

Report Available

1 to 3 days

Reporting Name

IgG/Albumin Ratio, CSF

Reference Values

CSF IgG: 0.0-8.1 mg/dL

CSF albumin: 0.0-27.0 mg/dL

CSF IgG/albumin: 0.00-0.21

Reference values have not been established for patients younger than 18 years.

Method Name

Nephelometry

Performing Laboratory

Mayo Clinic Laboratories in Rochester

CPT Code Information

82042

82784