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HelpTest Code APGH Alpha-Subunit Pituitary Tumor Marker, Serum
Ordering Guidance
This test should not be ordered on pregnant patients.
Specimen Required
Collection Container/Tube:
Preferred: Serum gel
Acceptable: Red top
Submission Container/Tube: Plastic vial
Specimen Volume: 1 mL
Collection Instructions: Centrifuge and aliquot serum into a plastic vial
CMH COLLECTION: 1mL blood in a Red vacutainer
Specimen Minimum Volume
0.35 mL
Specimen Stability Information
| Specimen Type | Temperature | Time | Special Container |
|---|---|---|---|
| Serum | Frozen (preferred) | 90 days | |
| Refrigerated | 7 days |
Useful For
Adjunct in the diagnosis of pituitary tumors
As part of the follow-up of treated pituitary tumor patients
Differential diagnosis of thyrotropin-secreting pituitary tumor versus thyroid hormone resistance
Differential diagnosis of constitutional delay of puberty versus hypogonadotrophic hypogonadism
Reject Due To
| Gross hemolysis | Reject |
| Gross lipemia | OK |
| Gross icterus | OK |
Day(s) Performed
Sunday
Report Available
2 to 8 daysReporting Name
AlphaSubunit Pituitary Tumor MarkerReference Values
PEDIATRIC
≤5 days: ≤50 ng/mL
6 days-12 weeks: ≤10 ng/mL
3 months-17 years: ≤1.2 ng/mL
Tanner II-IV*: ≤1.2 ng/mL
ADULTS
Males: ≤0.5 ng/mL
Premenopausal females: ≤1.2 ng/mL
Postmenopausal females: ≤1.8 ng/mL
Pediatric and adult reference values based on Mayo studies.
*Puberty onset (transition from Tanner stage I to Tanner stage II) occurs for boys at a median age of 11.5 (±2) years and for girls at a median age of 10.5 (±2) years. There is evidence that it may occur up to 1 year earlier in obese girls and in African American girls. For boys, there is no proven relationship between puberty onset and body weight or ethnic origin. Progression through Tanner stages is variable. Tanner stage V (adult) should be reached by age 18.
Method Name
Immunochemiluminescent Assay
Performing Laboratory
Mayo Clinic Laboratories in Rochester
CPT Code Information
82397