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HelpTest Code ANCA Cytoplasmic Neutrophil Antibodies, Serum
Additional Testing Requirements
When used for diagnosis, it is recommended that specific tests for proteinase 3 antibodies and myeloperoxidase antibodies be performed first, with additional testing for anti-neutrophil cytoplasmic antibodies only needed in certain circumstances.(3) A testing algorithm based on these recommendations is available. For more information see VASC / Antineutrophil Cytoplasmic Antibodies Vasculitis Panel, Serum.
Specimen Required
Supplies: Sarstedt Aliquot Tube, 5 mL (T914)
Collection Container/Tube:
Preferred: Serum gel
Acceptable: Red top
Submission Container/Tube: Plastic vial
Specimen Volume: 0.8 mL
Collection Instructions: Centrifuge and aliquot serum into plastic vial.
CMH COLLECTION: 1.5 mL in red gel vacutainer
Specimen Minimum Volume
0.4 mL
Specimen Stability Information
| Specimen Type | Temperature | Time | Special Container |
|---|---|---|---|
| Serum | Refrigerated (preferred) | 21 days | |
| Frozen | 21 days |
Testing Algorithm
For more information see:
-First-Line Screening for Autoimmune Liver Disease Algorithm.
Useful For
Evaluating patients with clinical features of ANCA-associated vasculitis, specifically granulomatosus with polyangiitis, microscopic polyangiitis, and eosinophilic granulomatosus with polyangiitis
Reject Due To
| Gross hemolysis | Reject |
| Gross lipemia | Reject |
| Gross icterus | OK |
| Heat-treated specimen | Reject |
Day(s) Performed
Monday through Saturday
Report Available
3 to 4 daysReporting Name
Cytoplasmic Neutrophilic Ab, SReference Values
<1:4 (Negative)
Method Name
Indirect Immunofluorescence (IIF)
Performing Laboratory
Mayo Clinic Laboratories in Rochester
CPT Code Information
86036 x2
86037-Titer (if appropriate)